GFRA2 FISH Probe
The GFRA2 FISH probe is designed to hybridize to the GFRA2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GFRA2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GFRA2-20-RE | 20 (40 μL) | 200 μL |  |
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| GFRA2-20-GO | 20 (40 μL) | 200 μL |  |
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| GFRA2-20-GR | 20 (40 μL) | 200 μL |  |
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| GFRA2-20-AQ | 20 (40 μL) | 200 μL |  |
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| GFRA2-20-DIG | 20 (40 μL) | 200 μL |  |
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| GFRA2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Gene Details
Gene Symbol: GFRA2
Gene Name: GDNF Family Receptor Alpha 2
Chromosome: CHR8: 21549529-21646346
Locus: 8p21.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GFRA2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GFRA2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping