GFRA1 Break Apart FISH Probe
Empire Genomics’ GFRA1 Break Apart FISH Probe is designed to flank the GFRA1 gene and is typically used for detecting GFRA1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GFRA1BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| GFRA1BA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| GFRA1BA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| GFRA1BA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| GFRA1BA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| GFRA1BA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| GFRA1BA-20-ORGR | 20 (40 μL) | 200 μL |
|
|
| GFRA1BA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| GFRA1BA-20-REGR | 20 (40 μL) | 200 μL |
|
Gene Summary
This gene encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
Gene Details
Gene Symbol: GFRA1
Gene Name: GDNF Family Receptor Alpha 1
Chromosome: CHR10: 117816441-118033126
Locus: 10q25.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: GFRA1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GFRA1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping