GEN1 Break Apart FISH Probe
Empire Genomics’ GEN1 Break Apart FISH Probe is designed to flank the GEN1 gene and is typically used for detecting GEN1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GEN1BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| GEN1BA-20-AQOR | 20 (40 μL) | 200 μL |
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| GEN1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| GEN1BA-20-GORE | 20 (40 μL) | 200 μL |
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| GEN1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| GEN1BA-20-GROR | 20 (40 μL) | 200 μL |
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| GEN1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| GEN1BA-20-REGO | 20 (40 μL) | 200 μL |
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| GEN1BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a member of the Rad2/xeroderma pigmentosum group G nuclease family, whose members are characterized by N-terminal and internal xeroderma pigmentosum group G nuclease domains followed by helix-hairpin-helix domains and disordered C-terminal domains. The protein encoded by this gene is involved in resolution of Holliday junctions, which are intermediate four-way structures that covalently link DNA during homologous recombination and double-strand break repair. The protein resolves Holliday junctions by creating dual incisions across the junction to produce nicked duplex products that can be ligated. In addition, this protein has been found to localize to centrosomes where it has been implicated in regulation of centrosome integrity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]
Gene Details
Gene Symbol: GEN1
Gene Name: GEN1, Holliday Junction 5' Flap Endonuclease
Chromosome: CHR2: 17935176-17966632
Locus: 2p24.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GEN1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GEN1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping