GCSH Break Apart FISH Probe
Empire Genomics’ GCSH Break Apart FISH Probe is designed to flank the GCSH gene and is typically used for detecting GCSH rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GCSHBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| GCSHBA-20-AQOR | 20 (40 μL) | 200 μL |
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| GCSHBA-20-GOGR | 20 (40 μL) | 200 μL |
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| GCSHBA-20-GORE | 20 (40 μL) | 200 μL |
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| GCSHBA-20-GRGO | 20 (40 μL) | 200 μL |
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| GCSHBA-20-GRRE | 20 (40 μL) | 200 μL |
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| GCSHBA-20-ORGR | 20 (40 μL) | 200 μL |
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| GCSHBA-20-REGO | 20 (40 μL) | 200 μL |
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| GCSHBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.[provided by RefSeq, Jan 2010]
Gene Details
Gene Symbol: GCSH
Gene Name: Glycine Cleavage System Protein H
Chromosome: CHR16: 81115551-81129980
Locus: 16q23.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GCSH FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GCSH-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping