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GCSH FISH Probe

The GCSH FISH probe is designed to hybridize to the GCSH gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
GCSH-20-OR  (Standard Design) 20 (40 μL) 200 μL
GCSH-20-RE 20 (40 μL) 200 μL
GCSH-20-GO 20 (40 μL) 200 μL
GCSH-20-GR 20 (40 μL) 200 μL
GCSH-20-AQ 20 (40 μL) 200 μL
GCSH-20-DIG 20 (40 μL) 200 μL
GCSH-20-BIO 20 (40 μL) 200 μL

Gene Summary

Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.[provided by RefSeq, Jan 2010]

Gene Details

Gene Symbol: GCSH

Gene Name: Glycine Cleavage System Protein H

Chromosome: CHR16: 81115551-81129980

Locus: 16q23.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: GCSH FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: GCSH-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping