GCLC Break Apart FISH Probe
Empire Genomics’ GCLC Break Apart FISH Probe is designed to flank the GCLC gene and is typically used for detecting GCLC rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GCLCBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| GCLCBA-20-AQOR | 20 (40 μL) | 200 μL |
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| GCLCBA-20-GOGR | 20 (40 μL) | 200 μL |
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| GCLCBA-20-GORE | 20 (40 μL) | 200 μL |
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| GCLCBA-20-GRGO | 20 (40 μL) | 200 μL |
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| GCLCBA-20-GRRE | 20 (40 μL) | 200 μL |
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| GCLCBA-20-ORGR | 20 (40 μL) | 200 μL |
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| GCLCBA-20-REGO | 20 (40 μL) | 200 μL |
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| GCLCBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct 2010]
Gene Details
Gene Symbol: GCLC
Gene Name: Glutamate-cysteine Ligase Catalytic Subunit
Chromosome: CHR6: 53362139-53409927
Locus: 6p12.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GCLC FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GCLC-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping