GCLC FISH Probe
The GCLC FISH probe is designed to hybridize to the GCLC gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GCLC-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GCLC-20-RE | 20 (40 μL) | 200 μL |  |
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| GCLC-20-GO | 20 (40 μL) | 200 μL |  |
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| GCLC-20-GR | 20 (40 μL) | 200 μL |  |
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| GCLC-20-AQ | 20 (40 μL) | 200 μL |  |
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| GCLC-20-DIG | 20 (40 μL) | 200 μL |  |
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| GCLC-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct 2010]
Gene Details
Gene Symbol: GCLC
Gene Name: Glutamate-cysteine Ligase Catalytic Subunit
Chromosome: CHR6: 53362139-53409927
Locus: 6p12.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: GCLC FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GCLC-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping