GCK Break Apart FISH Probe
Empire Genomics’ GCK Break Apart FISH Probe is designed to flank the GCK gene and is typically used for detecting GCK rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GCKBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| GCKBA-20-AQOR | 20 (40 μL) | 200 μL |
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| GCKBA-20-GOGR | 20 (40 μL) | 200 μL |
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| GCKBA-20-GORE | 20 (40 μL) | 200 μL |
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| GCKBA-20-GRGO | 20 (40 μL) | 200 μL |
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| GCKBA-20-GRRE | 20 (40 μL) | 200 μL |
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| GCKBA-20-ORGR | 20 (40 μL) | 200 μL |
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| GCKBA-20-REGO | 20 (40 μL) | 200 μL |
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| GCKBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a member of the hexokinase family of proteins. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. The use of multiple promoters and alternative splicing of this gene result in distinct protein isoforms that exhibit tissue-specific expression in the pancreas and liver. In the pancreas, this enzyme plays a role in glucose-stimulated insulin secretion, while in the liver, this enzyme is important in glucose uptake and conversion to glycogen. Mutations in this gene that alter enzyme activity have been associated with multiple types of diabetes and hyperinsulinemic hypoglycemia. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: GCK
Gene Name: Glucokinase
Chromosome: CHR7: 44183869-44229022
Locus: 7p13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GCK FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GCK-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping