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GB16860 FISH Probe

The GB16860 FISH probe is designed to hybridize to the GB16860 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
UHRF1-20-OR  (Standard Design) 20 (40 μL) 200 μL
UHRF1-20-RE 20 (40 μL) 200 μL
UHRF1-20-GO 20 (40 μL) 200 μL
UHRF1-20-GR 20 (40 μL) 200 μL
UHRF1-20-AQ 20 (40 μL) 200 μL
UHRF1-20-DIG 20 (40 μL) 200 μL
UHRF1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. It is regarded as a hub protein for the integration of epigenetic information. This gene is up-regulated in various cancers, and it is therefore considered to be a therapeutic target. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene exists on chromosome 12. [provided by RefSeq, Feb 2014]

Gene Details

Gene Symbol: UHRF1

Gene Name: Ubiquitin Like With PHD And Ring Finger Domains 1

Chromosome: CHR19: 4909509-4962165

Locus: 19p13.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: GB16860 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: UHRF1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping