GB12 FISH Probe
The GB12 FISH probe is designed to hybridize to the GB12 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CTCF-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CTCF-20-RE | 20 (40 μL) | 200 μL |  |
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| CTCF-20-GO | 20 (40 μL) | 200 μL |  |
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| CTCF-20-GR | 20 (40 μL) | 200 μL |  |
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| CTCF-20-AQ | 20 (40 μL) | 200 μL |  |
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| CTCF-20-DIG | 20 (40 μL) | 200 μL |  |
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| CTCF-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
Gene Details
Gene Symbol: CTCF
Gene Name: CCCTC-binding Factor
Chromosome: CHR16: 67596309-67673088
Locus: 16q22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GB12 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CTCF-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping