GAS5 Break Apart FISH Probe
Empire Genomics’ GAS5 Break Apart FISH Probe is designed to flank the GAS5 gene and is typically used for detecting GAS5 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GAS5BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| GAS5BA-20-AQOR | 20 (40 μL) | 200 μL |
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| GAS5BA-20-GOGR | 20 (40 μL) | 200 μL |
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| GAS5BA-20-GORE | 20 (40 μL) | 200 μL |
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| GAS5BA-20-GRGO | 20 (40 μL) | 200 μL |
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| GAS5BA-20-GRRE | 20 (40 μL) | 200 μL |
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| GAS5BA-20-ORGR | 20 (40 μL) | 200 μL |
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| GAS5BA-20-REGO | 20 (40 μL) | 200 μL |
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| GAS5BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene produces a spliced long non-coding RNA and is a member of the 5' terminal oligo-pyrimidine class of genes. It is a small nucleolar RNA host gene, containing multiple C/D box snoRNA genes in its introns. Part of the secondary RNA structure of the encoded transcript mimics glucocorticoid response element (GRE) which means it can bind to the DNA binding domain of the glucocorticoid receptor (nuclear receptor subfamily 3, group C, member 1). This action blocks the glucocorticoid receptor from being activated and thereby stops it from regulating the transcription of its target genes. This transcript is also thought to regulate the transcriptional activity of other receptors, such as androgen, progesterone and mineralocorticoid receptors, that can bind to its GRE mimic region. Multiple functions have been associated with this transcript, including cellular growth arrest and apoptosis. It has also been identified as a potential tumor suppressor, with its down-regulation associated with cancer in multiple different tissues. [provided by RefSeq, Mar 2015]
Gene Details
Gene Symbol: GAS5
Gene Name: Growth Arrest Specific 5 (non-protein Coding)
Chromosome: CHR1: 173833038-173837125
Locus: 1q25.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GAS5 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GAS5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping