GAPL FISH Probe
The GAPL FISH probe is designed to hybridize to the GAPL gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RASA4-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| RASA4-20-RE | 20 (40 μL) | 200 μL |  |
|
| RASA4-20-GO | 20 (40 μL) | 200 μL |  |
|
| RASA4-20-GR | 20 (40 μL) | 200 μL |  |
|
| RASA4-20-AQ | 20 (40 μL) | 200 μL |  |
|
| RASA4-20-DIG | 20 (40 μL) | 200 μL |  |
|
| RASA4-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: RASA4
Gene Name: RAS P21 Protein Activator 4
Chromosome: CHR7: 102220092-102257205
Locus: 7q22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: GAPL FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RASA4-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping