GAPDH FISH Probe
The GAPDH FISH probe is designed to hybridize to the GAPDH gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GAPDH-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GAPDH-20-RE | 20 (40 μL) | 200 μL |  |
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| GAPDH-20-GO | 20 (40 μL) | 200 μL |  |
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| GAPDH-20-GR | 20 (40 μL) | 200 μL |  |
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| GAPDH-20-AQ | 20 (40 μL) | 200 μL |  |
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| GAPDH-20-DIG | 20 (40 μL) | 200 μL |  |
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| GAPDH-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Many pseudogenes similar to this locus are present in the human genome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Gene Details
Gene Symbol: GAPDH
Gene Name: Glyceraldehyde-3-phosphate Dehydrogenase
Chromosome: CHR12: 6643656-6647536
Locus: 12p13.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GAPDH FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GAPDH-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping