GALR-2 FISH Probe
The GALR-2 FISH probe is designed to hybridize to the GALR-2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GALR2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GALR2-20-RE | 20 (40 μL) | 200 μL |  |
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| GALR2-20-GO | 20 (40 μL) | 200 μL |  |
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| GALR2-20-GR | 20 (40 μL) | 200 μL |  |
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| GALR2-20-AQ | 20 (40 μL) | 200 μL |  |
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| GALR2-20-DIG | 20 (40 μL) | 200 μL |  |
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| GALR2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: GALR2
Gene Name: Galanin Receptor 2
Chromosome: CHR17: 74070891-74073573
Locus: 17q25.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GALR-2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GALR2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping