GALE Break Apart FISH Probe
Empire Genomics’ GALE Break Apart FISH Probe is designed to flank the GALE gene and is typically used for detecting GALE rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| GALEBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| GALEBA-20-AQOR | 20 (40 μL) | 200 μL |
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| GALEBA-20-GOGR | 20 (40 μL) | 200 μL |
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| GALEBA-20-GORE | 20 (40 μL) | 200 μL |
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| GALEBA-20-GRGO | 20 (40 μL) | 200 μL |
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| GALEBA-20-GRRE | 20 (40 μL) | 200 μL |
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| GALEBA-20-ORGR | 20 (40 μL) | 200 μL |
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| GALEBA-20-REGO | 20 (40 μL) | 200 μL |
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| GALEBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and cognitive disability, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: GALE
Gene Name: UDP-galactose-4-epimerase
Chromosome: CHR1: 24122088-24127294
Locus: 1p36.11
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GALE FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GALE-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping