GAK FISH Probe
The GAK FISH probe is designed to hybridize to the GAK gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GAK-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GAK-20-RE | 20 (40 μL) | 200 μL |  |
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| GAK-20-GO | 20 (40 μL) | 200 μL |  |
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| GAK-20-GR | 20 (40 μL) | 200 μL |  |
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| GAK-20-AQ | 20 (40 μL) | 200 μL |  |
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| GAK-20-DIG | 20 (40 μL) | 200 μL |  |
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| GAK-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
Gene Details
Gene Symbol: GAK
Gene Name: Cyclin G Associated Kinase
Chromosome: CHR4: 843064-926174
Locus: 4p16.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GAK FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GAK-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping