SEARCH OUR PRODUCT CATALOG

FISH Probe Products & Services
Request More Information

GAB2 Break Apart FISH Probe

Empire Genomics’ GAB2 Break Apart FISH Probe is designed to flank the GAB2 gene and is typically used for detecting GAB2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping
Download Datasheet Download FISH Protocol Download Material Safety Data Sheet

SKU Test Kits Buffer Dye Color Order Now
GAB2BA-20-GROR  (Standard Design) 20 (40 μL) 200 μL
GAB2BA-20-AQOR 20 (40 μL) 200 μL
GAB2BA-20-GOGR 20 (40 μL) 200 μL
GAB2BA-20-GORE 20 (40 μL) 200 μL
GAB2BA-20-GRGO 20 (40 μL) 200 μL
GAB2BA-20-GRRE 20 (40 μL) 200 μL
GAB2BA-20-ORGR 20 (40 μL) 200 μL
GAB2BA-20-REGO 20 (40 μL) 200 μL
GAB2BA-20-REGR 20 (40 μL) 200 μL

Gene Summary

This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2009]

Gene Details

Gene Symbol: GAB2

Gene Name: GRB2 Associated Binding Protein 2

Chromosome: CHR11: 77926335-78128868

Locus: 11q14.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Distinct Patterns of Acral Melanoma Based on Site and Relative Sun Exposure

Acral melanomas vary considerably in their molecular, histological, and clinical presentation. In this study, acral melanomas from dorsal, volar, and subungual-interdigital body sites were assessed using several tests, including FISH. Our TERT, CCND1, CDK4, AURKA, CDKN2A, PAK1, PTEN, NF1, and GAB2 probes were used to detect copy number variations in these genes. Genetic profiles were found to be tightly tied to UV exposure.
Read More

Distinct Patterns of Acral Melanoma Based on Site and Relative Sun Exposure

Acral melanomas vary considerably in their molecular, histological, and clinical presentation. In this study, acral melanomas from dorsal, volar, and subungual-interdigital body sites were assessed using several tests, including FISH. Our TERT, CCND1, CDK4, AURKA, CDKN2A, PAK1, PTEN, NF1, and GAB2 probes were used to detect copy number variations in these genes. Genetic profiles were found to be tightly tied to UV exposure.
Read More

Product Details

Product: GAB2 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: GAB2-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping