G-22K FISH Probe
The G-22K FISH probe is designed to hybridize to the G-22K gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RAP1A-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RAP1A-20-RE | 20 (40 μL) | 200 μL |  |
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| RAP1A-20-GO | 20 (40 μL) | 200 μL |  |
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| RAP1A-20-GR | 20 (40 μL) | 200 μL |  |
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| RAP1A-20-AQ | 20 (40 μL) | 200 μL |  |
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| RAP1A-20-DIG | 20 (40 μL) | 200 μL |  |
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| RAP1A-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. The encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Gene Details
Gene Symbol: RAP1A
Gene Name: RAP1A, Member Of RAS Oncogene Family
Chromosome: CHR1: 112162404-112256101
Locus: 1p13.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: G-22K FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RAP1A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping