FRAXF FISH Probe
The FRAXF FISH probe is designed to hybridize to the FRAXF gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TMEM185A-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TMEM185A-20-RE | 20 (40 μL) | 200 μL |  |
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| TMEM185A-20-GO | 20 (40 μL) | 200 μL |  |
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| TMEM185A-20-GR | 20 (40 μL) | 200 μL |  |
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| TMEM185A-20-AQ | 20 (40 μL) | 200 μL |  |
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| TMEM185A-20-DIG | 20 (40 μL) | 200 μL |  |
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| TMEM185A-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is predicted to be a transmembrane protein. This gene is best known for localizing to the CpG island of the fragile site FRAXF. The 5' untranslated region of this gene contains a CGG trinucleotide repeat sequence that normally consists of 7-40 tandem CGG repeats but which can expand to greater than 300 repeats. Methylation of the CpG island leads to transcriptional silencing of this gene, but neither the silencing nor an expanded repeat region appear to manifest itself in a clear phenotypic manner. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Aug 2013]
Gene Details
Gene Symbol: TMEM185A
Gene Name: Transmembrane Protein 185A
Chromosome: CHRX: 148678215-148713487
Locus: Xq28
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: FRAXF FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TMEM185A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping