FRA3B FISH Probe
The FRA3B FISH probe is designed to hybridize to the FRA3B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FHIT-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| FHIT-20-RE | 20 (40 μL) | 200 μL |  |
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| FHIT-20-GO | 20 (40 μL) | 200 μL |  |
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| FHIT-20-GR | 20 (40 μL) | 200 μL |  |
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| FHIT-20-AQ | 20 (40 μL) | 200 μL |  |
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| FHIT-20-DIG | 20 (40 μL) | 200 μL |  |
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| FHIT-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a P1-P3-bis(5'-adenosyl) triphosphate hydrolase involved in purine metabolism. This gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. The encoded protein is also a tumor suppressor, as loss of its activity results in replication stress and DNA damage. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: FHIT
Gene Name: Fragile Histidine Triad
Chromosome: CHR3: 59735035-61237133
Locus: 3p14.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: FRA3B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: FHIT-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping