FPGT FISH Probe
The FPGT FISH probe is designed to hybridize to the FPGT gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FPGT-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| FPGT-20-RE | 20 (40 μL) | 200 μL |  |
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| FPGT-20-GO | 20 (40 μL) | 200 μL |  |
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| FPGT-20-GR | 20 (40 μL) | 200 μL |  |
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| FPGT-20-AQ | 20 (40 μL) | 200 μL |  |
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| FPGT-20-DIG | 20 (40 μL) | 200 μL |  |
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| FPGT-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose. There are two alternate pathways for the biosynthesis of GDP-fucose; the major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose. The protein encoded by this gene participates in an alternate pathway that is present in certain mammalian tissues, such as liver and kidney, and appears to function as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate, and then condensation of the beta-L-fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream TNNI3 interacting kinase (TNNI3K) gene. [provided by RefSeq, Dec 2010]
Gene Details
Gene Symbol: FPGT
Gene Name: Fucose-1-phosphate Guanylyltransferase
Chromosome: CHR1: 74663895-74674148
Locus: 1p31.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: FPGT FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: FPGT-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping