FOP FISH Probe
The FOP FISH probe is designed to hybridize to the FOP gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
FGFR1OP-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
FGFR1OP-20-RE | 20 (40 μL) | 200 μL | ||
FGFR1OP-20-GO | 20 (40 μL) | 200 μL | ||
FGFR1OP-20-GR | 20 (40 μL) | 200 μL | ||
FGFR1OP-20-AQ | 20 (40 μL) | 200 μL | ||
FGFR1OP-20-DIG | 20 (40 μL) | 200 μL | ||
FGFR1OP-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified. [provided by RefSeq, Jul 2013]
Gene Details
Gene Symbol: FGFR1OP
Gene Name: FGFR1 Oncogene Partner
Chromosome: CHR6: 167412815-167454066
Locus: 6q27
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
---|
Customer Publications
Product Details
Product: FOP FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: FGFR1OP-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping