FOLH1 Break Apart FISH Probe
Empire Genomics’ FOLH1 Break Apart FISH Probe is designed to flank the FOLH1 gene and is typically used for detecting FOLH1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FOLH1BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| FOLH1BA-20-AQOR | 20 (40 μL) | 200 μL |
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| FOLH1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| FOLH1BA-20-GORE | 20 (40 μL) | 200 μL |
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| FOLH1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| FOLH1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| FOLH1BA-20-ORGR | 20 (40 μL) | 200 μL |
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| FOLH1BA-20-REGO | 20 (40 μL) | 200 μL |
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| FOLH1BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. [provided by RefSeq, Jul 2010]
Gene Details
Gene Symbol: FOLH1
Gene Name: Folate Hydrolase 1
Chromosome: CHR11: 49168186-49230222
Locus: 11p11.12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: FOLH1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: FOLH1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping