FNK FISH Probe
The FNK FISH probe is designed to hybridize to the FNK gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PLK3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PLK3-20-RE | 20 (40 μL) | 200 μL |  |
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| PLK3-20-GO | 20 (40 μL) | 200 μL |  |
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| PLK3-20-GR | 20 (40 μL) | 200 μL |  |
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| PLK3-20-AQ | 20 (40 μL) | 200 μL |  |
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| PLK3-20-DIG | 20 (40 μL) | 200 μL |  |
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| PLK3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the highly conserved polo-like kinase family of serine/threonine kinases. Members of this family are characterized by an amino-terminal kinase domain and a carboxy-terminal bipartite polo box domain that functions as a substrate-binding motif and a cellular localization signal. Polo-like kinases are important regulators of cell cycle progression. This gene has also been implicated in stress responses and double-strand break repair. In human cell lines, this protein is reported to associate with centrosomes in a microtubule-dependent manner, and during mitosis, the protein becomes localized to the mitotic apparatus. Expression of a kinase-defective mutant results in abnormal cell morphology caused by changes in microtubule dynamics and mitotic arrest followed by apoptosis. [provided by RefSeq, Sep 2015]
Gene Details
Gene Symbol: PLK3
Gene Name: Polo Like Kinase 3
Chromosome: CHR1: 45266035-45271667
Locus: 1p34.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: FNK FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PLK3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping