FMP27 FISH Probe
The FMP27 FISH probe is designed to hybridize to the FMP27 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
KIAA0100-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
KIAA0100-20-RE | 20 (40 μL) | 200 μL | ||
KIAA0100-20-GO | 20 (40 μL) | 200 μL | ||
KIAA0100-20-GR | 20 (40 μL) | 200 μL | ||
KIAA0100-20-AQ | 20 (40 μL) | 200 μL | ||
KIAA0100-20-DIG | 20 (40 μL) | 200 μL | ||
KIAA0100-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This gene was initially characterized in human as having high expression levels in breast carcinomas and breast cancer cell lines. This gene also has increased expression in prostrate cancer cells relative to normal prostrate tissues. Expression of this gene is negatively regulated by direct binding of the microRNA miR-195 to its 3' UTR. miR-195 has been shown to modulate the invasiveness of prostrate cancer cells and xenograft metastases by downgrading expression of this gene. In mouse, the protein encoded by this gene was identified as an antigen on acute monocytic leukemia cells. In human, alternative splicing results in multiple transcript variants encoding distinct isoforms; some of these isoforms are predicted to contain an RNA pol II promoter FMP27 protein domain and a Golgi-body-localization APT1 domain. [provided by RefSeq, Apr 2017]
Gene Details
Gene Symbol: KIAA0100
Gene Name:
Chromosome: CHR17: 26941457-26972177
Locus: 17q11.2
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: FMP27 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: KIAA0100-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping