FMO1 FISH Probe
The FMO1 FISH probe is designed to hybridize to the FMO1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FMO1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| FMO1-20-RE | 20 (40 μL) | 200 μL |  |
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| FMO1-20-GO | 20 (40 μL) | 200 μL |  |
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| FMO1-20-GR | 20 (40 μL) | 200 μL |  |
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| FMO1-20-AQ | 20 (40 μL) | 200 μL |  |
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| FMO1-20-DIG | 20 (40 μL) | 200 μL |  |
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| FMO1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
Gene Details
Gene Symbol: FMO1
Gene Name: Flavin Containing Monooxygenase 1
Chromosome: CHR1: 171217662-171255113
Locus: 1q24.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: FMO1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: FMO1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping