FLT3 Break Apart FISH Probe
Empire Genomics’ FLT3 Break Apart FISH Probe is designed to flank the FLT3 gene and is typically used for detecting FLT3 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FLT3BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| FLT3BA-20-AQOR | 20 (40 μL) | 200 μL |
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| FLT3BA-20-GOGR | 20 (40 μL) | 200 μL |
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| FLT3BA-20-GORE | 20 (40 μL) | 200 μL |
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| FLT3BA-20-GRGO | 20 (40 μL) | 200 μL |
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| FLT3BA-20-GRRE | 20 (40 μL) | 200 μL |
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| FLT3BA-20-ORGR | 20 (40 μL) | 200 μL |
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| FLT3BA-20-REGO | 20 (40 μL) | 200 μL |
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| FLT3BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jan 2015]
Gene Details
Gene Symbol: FLT3
Gene Name: Fms Related Tyrosine Kinase 3
Chromosome: CHR13: 28577410-28674729
Locus: 13q12.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: FLT3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: FLT3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping