FKBP1A FISH Probe
The FKBP1A FISH probe is designed to hybridize to the FKBP1A gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FKBP1A-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| FKBP1A-20-RE | 20 (40 μL) | 200 μL |  |
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| FKBP1A-20-GO | 20 (40 μL) | 200 μL |  |
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| FKBP1A-20-GR | 20 (40 μL) | 200 μL |  |
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| FKBP1A-20-AQ | 20 (40 μL) | 200 μL |  |
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| FKBP1A-20-DIG | 20 (40 μL) | 200 μL |  |
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| FKBP1A-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed. [provided by RefSeq, Sep 2008]
Gene Details
Gene Symbol: FKBP1A
Gene Name: FK506 Binding Protein 1A
Chromosome: CHR20: 1349620-1373816
Locus: 20p13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: FKBP1A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: FKBP1A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping