FHIT Break Apart FISH Probe
Empire Genomics’ FHIT Break Apart FISH Probe is designed to flank the FHIT gene and is typically used for detecting FHIT rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FHITBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| FHITBA-20-AQOR | 20 (40 μL) | 200 μL |
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| FHITBA-20-GOGR | 20 (40 μL) | 200 μL |
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| FHITBA-20-GORE | 20 (40 μL) | 200 μL |
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| FHITBA-20-GRGO | 20 (40 μL) | 200 μL |
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| FHITBA-20-GRRE | 20 (40 μL) | 200 μL |
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| FHITBA-20-ORGR | 20 (40 μL) | 200 μL |
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| FHITBA-20-REGO | 20 (40 μL) | 200 μL |
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| FHITBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene is a P1-P3-bis(5'-adenosyl) triphosphate hydrolase involved in purine metabolism. This gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. The encoded protein is also a tumor suppressor, as loss of its activity results in replication stress and DNA damage. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: FHIT
Gene Name: Fragile Histidine Triad
Chromosome: CHR3: 59735035-61237133
Locus: 3p14.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: FHIT FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: FHIT-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping