FGFR3 FISH Probe
The FGFR3 FISH probe is designed to hybridize to the FGFR3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FGFR3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| FGFR3-20-RE | 20 (40 μL) | 200 μL |  |
|
| FGFR3-20-GO | 20 (40 μL) | 200 μL |  |
|
| FGFR3-20-GR | 20 (40 μL) | 200 μL |  |
|
| FGFR3-20-AQ | 20 (40 μL) | 200 μL |  |
|
| FGFR3-20-DIG | 20 (40 μL) | 200 μL |  |
|
| FGFR3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: FGFR3
Gene Name: Fibroblast Growth Factor Receptor 3
Chromosome: CHR4: 1795038-1810599
Locus: 4p16.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: FGFR3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: FGFR3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping