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FGFR1IIIC FISH Probe

The FGFR1IIIC FISH probe is designed to hybridize to the FGFR1IIIC gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
FGFR1-20-OR  (Standard Design) 20 (40 μL) 200 μL
FGFR1-20-RE 20 (40 μL) 200 μL
FGFR1-20-GO 20 (40 μL) 200 μL
FGFR1-20-GR 20 (40 μL) 200 μL
FGFR1-20-AQ 20 (40 μL) 200 μL
FGFR1-20-DIG 20 (40 μL) 200 μL
FGFR1-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: FGFR1

Gene Name: Fibroblast Growth Factor Receptor 1

Chromosome: CHR8: 38268655-38326352

Locus: 8p11.23

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: FGFR1IIIC FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: FGFR1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping