FGB FISH Probe
The FGB FISH probe is designed to hybridize to the FGB gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FGB-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| FGB-20-RE | 20 (40 μL) | 200 μL |  |
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| FGB-20-GO | 20 (40 μL) | 200 μL |  |
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| FGB-20-GR | 20 (40 μL) | 200 μL |  |
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| FGB-20-AQ | 20 (40 μL) | 200 μL |  |
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| FGB-20-DIG | 20 (40 μL) | 200 μL |  |
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| FGB-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
Gene Details
Gene Symbol: FGB
Gene Name: Fibrinogen Beta Chain
Chromosome: CHR4: 155484131-155493915
Locus: 4q31.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: FGB FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: FGB-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping