FDPS Break Apart FISH Probe
Empire Genomics’ FDPS Break Apart FISH Probe is designed to flank the FDPS gene and is typically used for detecting FDPS rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FDPSBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| FDPSBA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| FDPSBA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| FDPSBA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| FDPSBA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| FDPSBA-20-GROR | 20 (40 μL) | 200 μL |
|
|
| FDPSBA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| FDPSBA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| FDPSBA-20-REGR | 20 (40 μL) | 200 μL |
|
Gene Summary
This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2008]
Gene Details
Gene Symbol: FDPS
Gene Name: Farnesyl Diphosphate Synthase
Chromosome: CHR1: 155278538-155290457
Locus: 1q22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: FDPS FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: FDPS-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping