FDPS FISH Probe
The FDPS FISH probe is designed to hybridize to the FDPS gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FDPS-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| FDPS-20-RE | 20 (40 μL) | 200 μL |  |
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| FDPS-20-GO | 20 (40 μL) | 200 μL |  |
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| FDPS-20-GR | 20 (40 μL) | 200 μL |  |
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| FDPS-20-AQ | 20 (40 μL) | 200 μL |  |
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| FDPS-20-DIG | 20 (40 μL) | 200 μL |  |
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| FDPS-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2008]
Gene Details
Gene Symbol: FDPS
Gene Name: Farnesyl Diphosphate Synthase
Chromosome: CHR1: 155278538-155290457
Locus: 1q22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: FDPS FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: FDPS-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping