FCGR3A Break Apart FISH Probe
Empire Genomics’ FCGR3A Break Apart FISH Probe is designed to flank the FCGR3A gene and is typically used for detecting FCGR3A rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FCGR3ABA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| FCGR3ABA-20-AQOR | 20 (40 μL) | 200 μL |
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| FCGR3ABA-20-GOGR | 20 (40 μL) | 200 μL |
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| FCGR3ABA-20-GORE | 20 (40 μL) | 200 μL |
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| FCGR3ABA-20-GRGO | 20 (40 μL) | 200 μL |
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| FCGR3ABA-20-GRRE | 20 (40 μL) | 200 μL |
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| FCGR3ABA-20-ORGR | 20 (40 μL) | 200 μL |
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| FCGR3ABA-20-REGO | 20 (40 μL) | 200 μL |
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| FCGR3ABA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: FCGR3A
Gene Name: Fc Fragment Of IgG Receptor IIIa
Chromosome: CHR1: 161511550-161520413
Locus: 1q23.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: FCGR3A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: FCGR3A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping