FBXO8 Break Apart FISH Probe
Empire Genomics’ FBXO8 Break Apart FISH Probe is designed to flank the FBXO8 gene and is typically used for detecting FBXO8 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
FBXO8BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL | ||
FBXO8BA-20-AQOR | 20 (40 μL) | 200 μL | ||
FBXO8BA-20-GOGR | 20 (40 μL) | 200 μL | ||
FBXO8BA-20-GORE | 20 (40 μL) | 200 μL | ||
FBXO8BA-20-GRGO | 20 (40 μL) | 200 μL | ||
FBXO8BA-20-GRRE | 20 (40 μL) | 200 μL | ||
FBXO8BA-20-ORGR | 20 (40 μL) | 200 μL | ||
FBXO8BA-20-REGO | 20 (40 μL) | 200 μL | ||
FBXO8BA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: FBXO8
Gene Name: F-box Protein 8
Chromosome: CHR4: 175157809-175205402
Locus: 4q34.1
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: FBXO8 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: FBXO8-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping