FBLN5 FISH Probe
The FBLN5 FISH probe is designed to hybridize to the FBLN5 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FBLN5-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| FBLN5-20-RE | 20 (40 μL) | 200 μL |  |
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| FBLN5-20-GO | 20 (40 μL) | 200 μL |  |
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| FBLN5-20-GR | 20 (40 μL) | 200 μL |  |
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| FBLN5-20-AQ | 20 (40 μL) | 200 μL |  |
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| FBLN5-20-DIG | 20 (40 μL) | 200 μL |  |
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| FBLN5-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: FBLN5
Gene Name: Fibulin 5
Chromosome: CHR14: 92335754-92414046
Locus: 14q32.12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: FBLN5 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: FBLN5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping