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FBLN5 FISH Probe

The FBLN5 FISH probe is designed to hybridize to the FBLN5 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
FBLN5-20-OR  (Standard Design) 20 (40 μL) 200 μL
FBLN5-20-RE 20 (40 μL) 200 μL
FBLN5-20-GO 20 (40 μL) 200 μL
FBLN5-20-GR 20 (40 μL) 200 μL
FBLN5-20-AQ 20 (40 μL) 200 μL
FBLN5-20-DIG 20 (40 μL) 200 μL
FBLN5-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: FBLN5

Gene Name: Fibulin 5

Chromosome: CHR14: 92335754-92414046

Locus: 14q32.12

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: FBLN5 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: FBLN5-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping