FAM111A Break Apart FISH Probe
Empire Genomics’ FAM111A Break Apart FISH Probe is designed to flank the FAM111A gene and is typically used for detecting FAM111A rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FAM111ABA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FAM111ABA-20-AQOR | 20 (40 μL) | 200 μL |
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| FAM111ABA-20-GOGR | 20 (40 μL) | 200 μL |
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| FAM111ABA-20-GORE | 20 (40 μL) | 200 μL |
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| FAM111ABA-20-GRGO | 20 (40 μL) | 200 μL |
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| FAM111ABA-20-GROR | 20 (40 μL) | 200 μL |
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| FAM111ABA-20-GRRE | 20 (40 μL) | 200 μL |
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| FAM111ABA-20-REGO | 20 (40 μL) | 200 μL |
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| FAM111ABA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene is cell-cycle regulated, and has nuclear localization. The C-terminal half of the protein shares homology with trypsin-like peptidases and it contains a PCNA-interacting peptide (PIP) box, that is necessary for its co-localization with proliferating cell nuclear antigen (PCNA). Reduced expression of this gene resulted in DNA replication defects, consistent with the demonstrated role for this gene in Simian Virus 40 (SV40) viral replication. Mutations in this gene have been associated with Kenny-Caffey syndrome (KCS) type 2 and the more severe osteocraniostenosis (OCS, also known as Gracile Bone Dysplasia), both characterized by short stature, hypoparathyroidism, bone development abnormalities, and hypocalcemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
Gene Details
Gene Symbol: FAM111A
Gene Name: Family With Sequence Similarity 111 Member A
Chromosome: CHR11: 58910317-58922511
Locus: 11q12.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: FAM111A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: FAM111A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping