FADD FISH Probe
The FADD FISH probe is designed to hybridize to the FADD gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FADD-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| FADD-20-RE | 20 (40 μL) | 200 μL |  |
|
| FADD-20-GO | 20 (40 μL) | 200 μL |  |
|
| FADD-20-GR | 20 (40 μL) | 200 μL |  |
|
| FADD-20-AQ | 20 (40 μL) | 200 μL |  |
|
| FADD-20-DIG | 20 (40 μL) | 200 μL |  |
|
| FADD-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: FADD
Gene Name: Fas Associated Via Death Domain
Chromosome: CHR11: 70049268-70053508
Locus: 11q13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: FADD FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: FADD-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping