FA-D2 FISH Probe
The FA-D2 FISH probe is designed to hybridize to the FA-D2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FANCD2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| FANCD2-20-RE | 20 (40 μL) | 200 μL |  |
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| FANCD2-20-GO | 20 (40 μL) | 200 μL |  |
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| FANCD2-20-GR | 20 (40 μL) | 200 μL |  |
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| FANCD2-20-AQ | 20 (40 μL) | 200 μL |  |
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| FANCD2-20-DIG | 20 (40 μL) | 200 μL |  |
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| FANCD2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Gene Details
Gene Symbol: FANCD2
Gene Name: Fanconi Anemia Complementation Group D2
Chromosome: CHR3: 10068112-10143614
Locus: 3p25.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: FA-D2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: FANCD2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping