F9 Break Apart FISH Probe
Empire Genomics’ F9 Break Apart FISH Probe is designed to flank the F9 gene and is typically used for detecting F9 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| F9BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| F9BA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| F9BA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| F9BA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| F9BA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| F9BA-20-GROR | 20 (40 μL) | 200 μL |
|
|
| F9BA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| F9BA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| F9BA-20-REGR | 20 (40 μL) | 200 μL |
|
Gene Summary
This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Sep 2015]
Gene Details
Gene Symbol: F9
Gene Name: Coagulation Factor IX
Chromosome: CHRX: 138612894-138645617
Locus: Xq27.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: F9 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: F9-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping