F9 FISH Probe
The F9 FISH probe is designed to hybridize to the F9 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
F9-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
F9-20-RE | 20 (40 μL) | 200 μL | ||
F9-20-GO | 20 (40 μL) | 200 μL | ||
F9-20-GR | 20 (40 μL) | 200 μL | ||
F9-20-AQ | 20 (40 μL) | 200 μL | ||
F9-20-DIG | 20 (40 μL) | 200 μL | ||
F9-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Sep 2015]
Gene Details
Gene Symbol: F9
Gene Name: Coagulation Factor IX
Chromosome: CHRX: 138612894-138645617
Locus: Xq27.1
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: F9 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: F9-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping