F8 FISH Probe
The F8 FISH probe is designed to hybridize to the F8 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| F8-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| F8-20-RE | 20 (40 μL) | 200 μL |  |
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| F8-20-GO | 20 (40 μL) | 200 μL |  |
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| F8-20-GR | 20 (40 μL) | 200 μL |  |
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| F8-20-AQ | 20 (40 μL) | 200 μL |  |
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| F8-20-DIG | 20 (40 μL) | 200 μL |  |
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| F8-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: F8
Gene Name: Coagulation Factor VIII
Chromosome: CHRX: 154064063-154250998
Locus: Xq28
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: F8 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: F8-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping