F2 FISH Probe
The F2 FISH probe is designed to hybridize to the F2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
F2-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
F2-20-RE | 20 (40 μL) | 200 μL | ||
F2-20-GO | 20 (40 μL) | 200 μL | ||
F2-20-GR | 20 (40 μL) | 200 μL | ||
F2-20-AQ | 20 (40 μL) | 200 μL | ||
F2-20-DIG | 20 (40 μL) | 200 μL | ||
F2-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
Gene Details
Gene Symbol: F2
Gene Name: Coagulation Factor II, Thrombin
Chromosome: CHR11: 46740742-46761056
Locus: 11p11.2
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: F2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: F2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping