F10 Break Apart FISH Probe
Empire Genomics’ F10 Break Apart FISH Probe is designed to flank the F10 gene and is typically used for detecting F10 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| F10BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| F10BA-20-AQOR | 20 (40 μL) | 200 μL |
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| F10BA-20-GOGR | 20 (40 μL) | 200 μL |
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| F10BA-20-GORE | 20 (40 μL) | 200 μL |
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| F10BA-20-GRGO | 20 (40 μL) | 200 μL |
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| F10BA-20-GROR | 20 (40 μL) | 200 μL |
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| F10BA-20-GRRE | 20 (40 μL) | 200 μL |
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| F10BA-20-REGO | 20 (40 μL) | 200 μL |
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| F10BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides. [provided by RefSeq, Aug 2015]
Gene Details
Gene Symbol: F10
Gene Name: Coagulation Factor X
Chromosome: CHR13: 113777112-113803843
Locus: 13q34
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: F10 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: F10-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping