F FISH Probe
The F FISH probe is designed to hybridize to the F gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| F7-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| F7-20-RE | 20 (40 μL) | 200 μL |  |
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| F7-20-GO | 20 (40 μL) | 200 μL |  |
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| F7-20-GR | 20 (40 μL) | 200 μL |  |
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| F7-20-AQ | 20 (40 μL) | 200 μL |  |
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| F7-20-DIG | 20 (40 μL) | 200 μL |  |
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| F7-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides. [provided by RefSeq, Aug 2015]
Gene Details
Gene Symbol: F7
Gene Name: Coagulation Factor VII
Chromosome: CHR13: 113760104-113774995
Locus: 13q34
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: F FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: F7-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping