ET-3 FISH Probe
The ET-3 FISH probe is designed to hybridize to the ET-3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EDN3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| EDN3-20-RE | 20 (40 μL) | 200 μL |  |
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| EDN3-20-GO | 20 (40 μL) | 200 μL |  |
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| EDN3-20-GR | 20 (40 μL) | 200 μL |  |
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| EDN3-20-AQ | 20 (40 μL) | 200 μL |  |
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| EDN3-20-DIG | 20 (40 μL) | 200 μL |  |
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| EDN3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]
Gene Details
Gene Symbol: EDN3
Gene Name: Endothelin 3
Chromosome: CHR20: 57875498-57901047
Locus: 20q13.32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ET-3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: EDN3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping