EST1C FISH Probe
The EST1C FISH probe is designed to hybridize to the EST1C gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SMG7-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SMG7-20-RE | 20 (40 μL) | 200 μL |  |
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| SMG7-20-GO | 20 (40 μL) | 200 μL |  |
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| SMG7-20-GR | 20 (40 μL) | 200 μL |  |
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| SMG7-20-AQ | 20 (40 μL) | 200 μL |  |
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| SMG7-20-DIG | 20 (40 μL) | 200 μL |  |
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| SMG7-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD); a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2011]
Gene Details
Gene Symbol: SMG7
Gene Name: SMG7, Nonsense Mediated MRNA Decay Factor
Chromosome: CHR1: 183441505-183523328
Locus: 1q25.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: EST1C FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SMG7-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping