ESR1 FISH Probe
The ESR1 FISH probe is designed to hybridize to the ESR1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
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| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ESR1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ESR1-20-RE | 20 (40 μL) | 200 μL |  |
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| ESR1-20-GO | 20 (40 μL) | 200 μL |  |
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| ESR1-20-GR | 20 (40 μL) | 200 μL |  |
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| ESR1-20-AQ | 20 (40 μL) | 200 μL |  |
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| ESR1-20-DIG | 20 (40 μL) | 200 μL |  |
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| ESR1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]
Gene Details
Gene Symbol: ESR1
Gene Name: Estrogen Receptor 1
Chromosome: CHR6: 152011630-152424408
Locus: 6q25.1-q25.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ESR1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ESR1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping