ESCRT-I FISH Probe
The ESCRT-I FISH probe is designed to hybridize to the ESCRT-I gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TSG101-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TSG101-20-RE | 20 (40 μL) | 200 μL |  |
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| TSG101-20-GO | 20 (40 μL) | 200 μL |  |
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| TSG101-20-GR | 20 (40 μL) | 200 μL |  |
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| TSG101-20-AQ | 20 (40 μL) | 200 μL |  |
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| TSG101-20-DIG | 20 (40 μL) | 200 μL |  |
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| TSG101-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: TSG101
Gene Name: Tumor Susceptibility 101
Chromosome: CHR11: 18501857-18548503
Locus: 11p15.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ESCRT-I FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TSG101-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping